Mutations in Proprotein Convertase Subtilisin Kexin 9 (PCSK9) have been associated with autosomal dominant hypercholesterolemia.In vivo kinetic studies indicate that LDL catabolism was impaired and apolipoprotein B (apoB)-containing lipoprotein synthesis was enhanced in two patients presenting with the S127R mutation on PCSK9.To understand the phys
Temperature and precipitation are expected to increase in the forthcoming decades in the northeastern Qinghai-Tibetan Plateau, with uncertain effects of their interaction on plant and soil carbon:nitrogen:phosphorus (C:N:P) stoichiometry in alpine ecosystems.A two-year field experiment was conducted to examine the effects of warming, precipitation
Introduction: Thoracic myelopathy due to ossification of the posterior longitudinal ligament (T-OPLL) is an indication for surgical treatment because the symptom is usually progressive.The surgery for T-OPLL is technically challenging for several reasons.Various operational procedures were developed for dealing with T-OPLL.The anterior decompressio